Ligand Info
In DepthDetails
Ligand Info
In DepthDetails
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 0.890nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
Ligand Info
In DepthDetails
Ligand Info
In DepthDetails
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate incubated for 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of PDE4B isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human U-937 cells derived PDE4B using [3H] cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of PDE4D isolated from human U937 cells using [3H]-cAMP incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDE4B derived from human monocytes using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate incubated for 5 mins followed by NADPH addition and measured after 5 m...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails